GHK-Cu

GHK-Cu (glycyl-L-histidyl-L-lysine copper complex) is a naturally occurring human tripeptide first isolated from plasma studies comparing young versus aging tissue. Its primary mechanism is broad gene regulation — resetting aging gene expression profiles toward healthier, younger states.

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Overview

GHK-Cu modulates over 4,000 human genes — upregulating regeneration, repair, and anti-inflammatory signaling while downregulating genes linked to inflammation and tissue destruction. Used in anti-aging, dermatology, and regenerative medicine as an adjunct to support skin, wound healing, collagen synthesis, hair, bone, and neurological health.

These statements have not been evaluated by the U.S. Food and Drug Administration and should not be interpreted as medical advice or a guarantee of treatment outcomes.

Key Benefits

Gene Expression Reset

Modulates over 4,000 genes — restoring expression patterns associated with younger tissue and suppressing genes linked to inflammation and destruction.

Skin & Collagen Renewal

Stimulates collagen, glycosaminoglycans, and decorin synthesis — supporting firmer, more elastic skin and well-organized connective tissue architecture.

Tissue Repair & Angiogenesis

Promotes new blood vessel formation to supply healing tissue, while activating DNA repair pathways and clearing damaged cellular proteins via the ubiquitin system.

Anti-Inflammatory & Antioxidant

Modulates copper redox activity to reduce free radical generation and dampens chronic low-grade inflammation — a primary driver of tissue aging.

Information presented here is for educational purposes only and not intended to replace or substitute guidance from a healthcare provider. Compounded products are not FDA-approved nor evaluated by the FDA for safety, efficacy, or quality. 

Simple. Medical. Personalized.

Medical intake

Answer a few online questions about your health history, lifestyle, and goals — no clinic visits required.

Provider evaluation

A licensed medical professional reviews your intake and determines the safest, most effective option for you.

Personalized plan

Custom treatment plan built around your unique health needs, goals, medical history, and biology.

Ongoing support

Stay connected with your care team for follow-ups, adjustments, and expert answers — all online.

FAQs

Administration

GHK-Cu is supplied as a lyophilized powder, reconstituted with bacteriostatic water before use, and administered subcutaneously. Dose, frequency, and treatment duration are determined entirely by your prescribing provider.

Precautions

GHK-Cu is not FDA-approved — all use is off-label and investigational. Not recommended in patients with active malignancy, Wilson's disease or copper metabolism disorders, pregnancy, breastfeeding, or benzyl alcohol sensitivity. Written informed consent is required. Disclose all medications and health conditions to your provider before starting.

Storage

Store unreconstituted vials refrigerated at 36°F–46°F (2°C–8°C), protected from light. Do not freeze. Once reconstituted, refrigerate and use within 28 days. Discard if cloudy or discolored. Keep out of reach of children.

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