Tissue Repair + Gut Healing

BPC-157

Protein found in human gastric juice with active role in tissue repair, angiogenesis, collagen synthesis, & anti-inflammatory pathways.

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  • Syringes Included

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🚫Shipping Restrictions: Pharmacy can NOT ship directly to the following states: Alabama, California, DC, Louisiana, Massachusetts, Michigan, Mississippi, Montana, Texas, Washington, and West Virginia.

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Overview

Pharmacology

15 amino acids, derived from a cytoprotective sequence found in human gastric juice. It is stable in gastric acid, orally bioavailable, and active at both local and systemic levels without requiring cofactors for activity. It does not bind to a single defined receptor but modulates multiple signaling pathways simultaneously,  including the nitric oxide system, growth factor receptors, and the dopaminergic and serotonergic systems. 

Mechanism of Action

Upregulates VEGFR2 and EGF receptor expression to promote angiogenesis and accelerate tissue vascularization at injury sites. Activates the FAK-paxillin pathway to enhance fibroblast migration and collagen deposition. Modulates NOS activity to increase local nitric oxide production and improve blood flow. Stabilizes the gut epithelial barrier by upregulating tight junction proteins including occludin and claudins. Interacts with dopamine D1/D2 receptors and serotonin transporter activity, influencing gut motility and stress response.

Injection

Administered subcutaneously. 15 mg per vial. 500 mcg per dose is 30 day supply of 15 mg vial.

Information presented here is for educational purposes only and not intended to replace or substitute guidance from a healthcare provider. Compounded products are not FDA-approved nor evaluated by the FDA for safety, efficacy, or quality.

Benefits

Musculoskeletal Repair

Stimulates collagen synthesis and fibroblast activity, which are foundational to connective tissue repair and recovery from repetitive strain.

GI Mucosal Healing

Derived from a cytoprotective sequence in human gastric juice, BPC-157 has direct affinity for gastrointestinal tissue — upregulating tight junction proteins to restore intestinal barrier integrity, reducing mucosal inflammation, and accelerating repair of the gut lining.

Anti-Inflammatory Modulation

Modulates macrophage activity and inflammatory cytokine expression, supporting the transition from acute inflammation toward the proliferative and remodeling phases of tissue repair.

Angiogenesis Support

Activates VEGFR2 signaling and the Akt-eNOS cascade, increasing nitric oxide production and promoting formation of new blood vessels to deliver oxygen and nutrients to damaged tissue.

Individual results may vary. Benefits described are based on clinical and pharmacological evidence and do not constitute a guarantee of treatment outcomes. All treatment requires evaluation and approval by a licensed provider.

Simple. Medical. Personalized.

Medical intake

Answer a few online questions about your health history, lifestyle, & goals. No clinic visits required.

Provider evaluation

A licensed medical provider reviews your intake to determine the safest, personalized treatment.

Personalized plan

Custom treatment plan built around your unique health needs, goals, medical history, & biology.

Ongoing support

Stay connected with your care team for follow-ups, adjustments, & expert answers 100% online.

FAQs

Does BPC-157 require a prescription?

Yes. Pentadeca Arginate (BPC-157) is a compounded prescription peptide dispensed pursuant to a valid prescription from a licensed healthcare provider. A telehealth consultation, written informed consent, and full medical intake are required before dispensing to confirm candidacy, establish an individualized protocol, and ensure the patient understands the off-label nature of this therapy.

What are the possible side effects?

Side effects with PDA are generally mild and consistent with peptide therapies in this class. These include injection site reactions (mild redness, swelling, or transient discomfort), transient GI changes including nausea or altered bowel habits, occasional headache or mild dizziness, and temporary fatigue or increased soreness at the targeted tissue during the initial treatment phase. Serious adverse effects have not been documented in available clinical reports at therapeutic doses. Contact your provider immediately if you experience persistent injection site reactions, signs of systemic allergic response, or any unusual symptoms.

Who should not use BPC-157?

PDA is not appropriate for patients with active malignancy or a history of malignancy without thorough oncological evaluation, as its angiogenic properties raise a theoretical concern regarding tumor vascular supply. Patients who are pregnant or breastfeeding should not use this compound, as safety data is absent. Those with active autoimmune conditions or on immunosuppressive therapy require individualized provider review. PDA has not been studied in patients under 18.

Are there any drug interactions?

Formal interaction studies have not been conducted. Patients on anticoagulants or antiplatelet agents (warfarin, heparin) should discuss concomitant use with their provider, as PDA's nitric oxide-mediated vasodilatory effects may have additive effects on vascular tone and platelet function. Patients on immunosuppressants require individualized evaluation due to PDA's immune-modulating activity. NSAIDs used concurrently may blunt the natural inflammatory phases that PDA is intended to support; providers may prefer to minimize NSAID use during therapy. Always provide a complete medication list before beginning treatment.

Is BPC-157 safe if I have a pre-existing medical condition?

Patients with any malignancy history must not use PDA without thorough oncological and provider review. Those with autoimmune conditions, cardiovascular disease, significant renal or hepatic impairment, or coagulation disorders require individualized assessment. Long-term human safety data is not established, and all clinical use is off-label. Your provider requires a complete medical history before prescribing and will evaluate whether PDA is appropriate given your specific clinical picture.

Start Your Journey

Repair Deeper.

Recover Faster.

Physician-supervised. Pharmacy ships to your door.

No clinic visits required.

  • Licensed Provider

  • Licensed Pharmacy

  • HIPAA Compliant

  • LegitScript Certified

Optimize Your Protocol

These treatments work synergistically with your current protocol to accelerate results and improve long-term outcomes.

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The information and products provided on this website are for educational and wellness purposes only and are not intended to diagnose, treat, cure, or prevent any disease. All treatments require evaluation and approval by a licensed healthcare provider through a telemedicine consultation. Individual results may vary, and products carry potential risks and side effects. Certain products may not be evaluated by the U.S. Food and Drug Administration (FDA) unless explicitly stated. Services are provided by licensed physicians and nurse practitioners in states where they are authorized to practice, including California, Florida, Nevada, and other participating states. This service is not intended for medical emergencies. If you are experiencing an emergency, call 911 or seek immediate medical care. We take reasonable measures to protect personal health information in accordance with applicable privacy laws, including HIPAA. By using this website or its services, you agree to our Terms of Service, Privacy Policy, and Telehealth Consent. You must be 18 years of age or older to use this service. We do not manufacture, handle, or ship medications.