
L-Carnitine Injection (Levocarnitine) is a compounded injectable form of the naturally occurring amino acid derivative carnitine. It is available through our 503A pharmacy pursuant to a valid patient-specific prescription from a licensed healthcare provider. As a compounded preparation, it is not an FDA-approved drug product, and FDA does not review compounded medications for safety, efficacy, or quality.
Concentration: 500 mg/mL Routes of Administration: Intravenous (IV) or Intramuscular (IM)
| Active Ingredient | Concentration |
|---|---|
| L-Carnitine (Levocarnitine) | 500 mg/mL |




Dosage: Determined by the prescribing healthcare provider on an individual basis. Do not adjust your dose or frequency without medical guidance.
Concentration: 500 mg/mL
Routes: Intravenous (IV) or Intramuscular (IM) injection, as directed by your provider.
Administration technique, injection site selection, and dosing schedule should all be reviewed with your healthcare provider or a qualified clinical staff member before beginning treatment.
L-Carnitine has two clinically significant drug interaction categories that patients and prescribers should be aware of before initiating therapy.
Pivalate-conjugated antibiotics (such as pivampicillin, used in the treatment of urinary tract infections) form conjugates with carnitine in the body, and the resulting pivaloyl-carnitine complexes are excreted in urine. This increases net carnitine loss and can lead to carnitine depletion with repeated or prolonged antibiotic use. Patients on these antibiotics should have carnitine levels monitored if concurrent levocarnitine therapy is indicated.
Certain anticonvulsant medications — including valproic acid, phenobarbital, phenytoin, and carbamazepine — have been associated with meaningfully reduced blood carnitine levels. Valproic acid in particular, whether used alone or in combination with other anticonvulsants, may also cause hepatotoxicity and elevated plasma ammonia, which can progress to encephalopathy. Patients on these medications who require carnitine supplementation should be monitored closely, and prescribers should be aware of this interaction when evaluating both conditions concurrently.
Inform your healthcare provider and pharmacist of all medications, supplements, and herbal preparations you are taking before beginning L-Carnitine Injection.
L-Carnitine Injection is generally well tolerated at therapeutic doses, but as with any injectable compound, certain adverse effects are possible and patients should be informed of what to watch for.
Common side effects may include nausea, vomiting, diarrhea, nasal congestion, restlessness, insomnia, and a characteristic body odor described as fishy. This odor results from the bacterial conversion of carnitine to trimethylamine in the gut and is more commonly associated with higher oral doses, though it can occur with injectable use as well.
Serious side effects are less common but require prompt medical attention if they occur. These include tachycardia (an abnormally elevated heart rate), hypertension (high blood pressure), and fever. If you experience any of these, discontinue use and contact your healthcare provider or seek medical care promptly.
Patients with a history of seizure disorders, renal impairment, or those taking any of the interacting medications listed above should discuss their full medical history with their prescriber before initiating therapy.
Store at controlled room temperature. Keep protected from direct light. Do not freeze. Inspect the vial visually before each use — the solution should be clear and free of particulate matter or discoloration. Do not use if the solution appears cloudy or has visible particles. Keep out of reach of children. Dispose of unused or expired medication through a pharmaceutical take-back program or in accordance with your pharmacy's guidance — do not flush or discard in household waste.

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