hair + skin + nails + Energy

Vitamin B-Complex

B1, B2, B3, B5, B6 vitamins in a single injectable. Supports energy, metabolism, immune function, and cellular health.

  • No Insurance Required

  • Ships From USA Pharmacy

  • Free Medical Consultation

  • Syringes Included

  • No Subscription Required

  • Licensed Provider

  • Licensed Pharmacy

  • HIPAA Compliant

  • LegitScript Certified

Overview

Pharmacology

This formulation delivers five water-soluble B vitamins — Thiamine (B1), Riboflavin (B2), Niacinamide (B3), Dexpanthenol (B5), and Pyridoxine (B6) — via intramuscular injection, bypassing the gastrointestinal absorption variability that limits oral supplementation. Because B vitamins are not stored in significant quantities, depletion occurs within weeks of inadequate intake, and subclinical deficiency is common even without overt clinical signs.

Mechanism of Action

Each B vitamin operates at a distinct enzymatic node, and their functions are interdependent — deficiency in one impairs the activation and utilization of others.

B1 (Thiamine → TPP): TPP is the obligate cofactor for pyruvate dehydrogenase, which converts pyruvate to acetyl-CoA — the entry point of aerobic glucose oxidation. Without adequate TPP, cells cannot efficiently extract energy from carbohydrates and revert to anaerobic pathways. TPP also drives alpha-ketoglutarate dehydrogenase in the TCA cycle and transketolase in the pentose phosphate pathway.

B2 (Riboflavin → FAD/FMN): FAD and FMN accept electrons at Complex I and Complex II of the mitochondrial electron transport chain, directly participating in ATP synthesis. Riboflavin also activates B6 and folate through FAD-dependent enzymes, and regenerates reduced glutathione via glutathione reductase — linking riboflavin status to cellular antioxidant defense.

B3 (Niacinamide → NAD+/NADP+): NAD+ accepts hydride ions at multiple steps in glycolysis, the TCA cycle, and fatty acid beta-oxidation — making it the most heavily consumed electron carrier in energy metabolism. NAD+ is also the substrate for sirtuin deacetylases (SIRT1–7), which regulate mitochondrial biogenesis, DNA repair, and cellular stress response. NADP+ drives the pentose phosphate pathway and provides reducing equivalents for biosynthesis and cytochrome P450-mediated detoxification. Unlike nicotinic acid, niacinamide does not cause vasodilatory flushing.

B5 (Dexpanthenol → CoA): Coenzyme A is the central metabolic hub linking carbohydrate, fat, and protein metabolism. Acetyl-CoA — the primary CoA thioester — feeds the TCA cycle, ketogenesis, fatty acid synthesis, and cholesterol biosynthesis. CoA is also required for synthesis of acetylcholine and steroid hormones, and for the acetylation of histones that regulate gene expression.

B6 (Pyridoxine → PLP): Pyridoxal-5'-phosphate participates in over 100 enzymatic reactions, more than any other coenzyme. It is the obligate cofactor for transamination (interconversion of amino acids), decarboxylation (synthesis of serotonin from tryptophan, dopamine from DOPA, GABA from glutamate, histamine from histidine), and glycogen phosphorylase (glycogenolysis during fasting or exercise). PLP deficiency produces broad neurological and metabolic dysfunction disproportionate to its apparent simplicity.

Injection

Administered via intramuscular injection for direct bioavailability, bypassing gastrointestinal absorption variability.

Information presented here is for educational purposes only and not intended to replace or substitute guidance from a healthcare provider. Compounded products are not FDA-approved nor evaluated by the FDA for safety, efficacy, or quality.

Benefits

Energy Production

B1, B2, B3, and B5 are each required at different stages of cellular energy metabolism. Deficiency in any one disrupts the conversion of carbohydrates, fats, and proteins into usable ATP.

Hair Health

B2 supports cellular energy production in hair follicles. B3 improves scalp circulation and nourishes follicular tissue. B5 supports adrenal function, which regulates stress-related hair loss. B6 supports keratin and melanin production.

Red Blood Cell Formation

B6 is a cofactor for hemoglobin synthesis. B2 supports the activation of B6 and folate pathways. Adequate levels are required to prevent anemia and maintain oxygen-carrying capacity.

Metabolism

B6 is a cofactor for transamination, decarboxylation, and deamination of amino acids. These reactions are essential for protein metabolism, muscle repair, and neurotransmitter production.

Mood and Stress

Required for the production of serotonin, dopamine, and GABA. Supports emotional balance, reduces irritability, and helps the body manage physical and mental stress.

Skin and Mucosal Health

B2 (riboflavin) and B3 (niacinamide) support epithelial cell turnover, mucosal integrity, and skin health.

Individual results may vary. Benefits described are based on clinical and pharmacological evidence and do not constitute a guarantee of treatment outcomes. All treatment requires evaluation and approval by a licensed provider.

Simple. Medical. Personalized.

Medical intake

Answer a few online questions about your health history, lifestyle, & goals. No clinic visits required.

Provider evaluation

A licensed medical provider reviews your intake to determine the safest, personalized treatment.

Personalized plan

Custom treatment plan built around your unique health needs, goals, medical history, & biology.

Ongoing support

Stay connected with your care team for follow-ups, adjustments, & expert answers 100% online.

FAQs

What is Vitamin B Complex?

Vitamin B Complex is a prescription therapy used for energy production and nervous system support.

Who should use Vitamin B Complex?

Patients seeking support for energy production and nervous system support may qualify after evaluation by a licensed provider.

Does Vitamin B-Complex require a prescription?

Yes. This injectable B-complex preparation is a compounded prescription medication dispensed pursuant to a valid prescription from a licensed healthcare provider. A telehealth consultation and medical intake are required to confirm suitability and establish the appropriate administration route, dosing, and frequency.

What are the possible side effects?

Injectable B-complex vitamins are generally well tolerated. Injection site reactions — mild redness, discomfort, or swelling — may occur with IM or subcutaneous administration. Some patients experience a warm sensation or mild flushing following IV administration, consistent with niacin's vasodilatory effects. Rare hypersensitivity reactions are possible; discontinue and seek medical attention immediately if you experience rash, difficulty breathing, or swelling following administration.

Who should not use Vitamin B-Complex?

Patients with known hypersensitivity to any component of the formulation — including any of the five B-vitamin forms — should not receive this preparation. Individuals with rare metabolic disorders affecting B-vitamin utilization require specialist evaluation. Patients who are pregnant or breastfeeding should discuss use with their provider, as dosing considerations differ in these populations. This preparation is intended for adult patients under provider supervision.

Are there any drug interactions?

High-dose pyridoxine (B6) can reduce the effectiveness of certain anticonvulsant medications including phenobarbital and phenytoin. Patients on levodopa without a dopa-decarboxylase inhibitor should not use B6-containing preparations, as B6 can interfere with levodopa's therapeutic effect. Niacinamide (B3) at therapeutic doses generally has minimal interaction risk, but patients on anticoagulants or lipid-modifying agents should disclose this to their provider. Always provide a complete medication list before beginning treatment.

Is Vitamin B-Complex safe if I have a pre-existing medical condition?

Patients with significant renal impairment should be evaluated carefully, as B-vitamins are renally cleared and accumulation is possible. Those with hepatic conditions should disclose their history, as B3 (niacinamide) is metabolized hepatically. Patients with active cardiovascular conditions or on multiple medications should have their complete health history reviewed before initiating injectable B-complex therapy.

Contact Us

Text or Call

Hours

Mon–Fri, 10am–8pm ET

Text or Call

Hours

Mon–Fri, 9am–6pm PST

Start Your Journey

Start Feeling Better Today

Physician-supervised. Delivered to your door. No clinic visits required.

  • Licensed Provider

  • Licensed Pharmacy

  • HIPAA Compliant

  • LegitScript Certified

Optimize Your Protocol

These treatments work synergistically with your current protocol to accelerate results and improve long-term outcomes.

L-Carnitine

$150

Methylcobalamin

$99

Tri-Immune Boost

$150

NAD+

$250

Comprehensive Micronutrient

$299

The information and clinical services described on this website are for educational and informational purposes only and are not intended to diagnose, treat, cure, or prevent any disease. All treatments require evaluation and approval by a licensed healthcare provider through a telemedicine consultation. Treatment approval is not guaranteed. Individual results may vary, and treatments may carry risks and side effects. Certain compounded medications, wellness treatments, or off-label uses may not be evaluated by the U.S. Food and Drug Administration (FDA) for safety, effectiveness, or quality unless explicitly stated. Testosterone Shots provides telehealth consultations, clinical review, care coordination, lab-related services, membership services, and ongoing treatment management. Testosterone Shots is not a pharmacy and does not manufacture, compound, dispense, sell, handle, warehouse, ship, or collect payment for prescription medication. Testosterone Shots collects payment only for consultations, clinical review, care coordination, lab-related services, membership services, and other non-pharmacy services. If treatment is approved, your prescription may be sent to a licensed pharmacy partner. The pharmacy contacts you directly to complete medication payment and shipping. Services are provided by licensed physicians, nurse practitioners, and/or other licensed healthcare providers in states where they are authorized to practice. This service is not intended for medical emergencies. If you are experiencing an emergency, call 911 or seek immediate medical care. We take reasonable measures to protect personal health information in accordance with applicable privacy laws, including HIPAA. By using this website or its services, you agree to our Terms of Service, Privacy Policy, Notice of Privacy Practices, Telehealth Consent, and Important Safety Information. You must be 18 years of age or older to use this service.