Dosing for Pregnyl® varies by indication and is determined entirely by your prescribing provider. For ovulation induction in women, a single precisely timed dose is typically administered to trigger the LH surge. For men with hypogonadism, injections are usually given on a regular schedule — often two to three times per week — over a course of weeks or months. Reconstitute the lyophilized powder with bacteriostatic water as directed and administer by subcutaneous or intramuscular injection. Rotate injection sites and use a new needle for each injection.

Pregnyl® is an FDA-approved prescription medication. It is contraindicated in patients with precocious puberty, hormone-sensitive cancers, uncontrolled thyroid or adrenal dysfunction, and in patients with hypersensitivity to HCG. In women, there is a risk of ovarian hyperstimulation syndrome (OHSS), particularly when used in conjunction with ovarian stimulation medications. Multiple gestation (twins or more) is also a known risk. In men, HCG can cause fluid retention and, in rare cases, gynecomastia. Consult your provider for the complete prescribing information and a full discussion of risks and benefits.

Store unreconstituted Pregnyl® powder at controlled room temperature, protected from light. Once reconstituted with bacteriostatic water, store the solution in the refrigerator at 36°F–46°F (2°C–8°C) and use within 30 days, or as directed on your prescription label. Do not freeze the reconstituted solution. Keep out of reach of children. Discard any unused solution after the recommended period. For complete prescribing information, refer to the official FDA-approved label.