Sperm Load + Natural T Boost

Gonadorelin Pregnenolone + DHEA

A three-active sublingual troche supporting natural testosterone production and adrenal androgen balance through daily HPG axis stimulation and steroidogenic precursor replenishment.

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Overview

Gonadorelin + Pregnenolone + DHEA

This troche addresses the three primary hormonal axes that decline together in aging men: pituitary GnRH signaling via gonadorelin, downstream steroidogenesis via pregnenolone, and adrenal androgen output via DHEA. Together they support the body's own capacity to produce and maintain optimal testosterone and neurosteroid levels through natural precursor and signaling pathways rather than direct hormone replacement.

Mechanism of Action

Gonadorelin stimulates pituitary GnRH receptors to maintain pulsatile LH and FSH secretion, preserving testicular testosterone biosynthesis and spermatogenesis through the HPG axis. Pregnenolone replenishes the master steroid precursor that feeds the entire steroidogenic cascade, converting to DHEA, progesterone, and sex hormone intermediates as needed. DHEA supplements adrenal androgen precursor output, serving as a direct substrate for peripheral testosterone and estrogen synthesis in target tissues.

Oral

Dissolve one troche under your tongue before bed

Information presented here is for educational purposes only and not intended to replace or substitute guidance from a healthcare provider. Compounded medications are not FDA-approved nor evaluated by the FDA for safety, efficacy, or quality.

Benefits

Energy

DHEA and pregnenolone replenish the adrenal androgen precursors responsible for daytime energy, mental clarity, and stress resilience that decline significantly after age 30.

Lean Muscle

Gonadorelin-sustained LH stimulation maintains intratesticular testosterone to support lean muscle preservation and body composition.

Mood and Stress

Pregnenolone exerts direct neurosteroid effects on GABA and NMDA receptor systems, supporting mood stability, cognitive function, and stress regulation.

Sexual Health

Restored hormonal precursor availability and sustained HPG axis activity support libido, energy, and sexual function naturally.

Fertility

Gonadorelin preserves FSH-driven Sertoli cell support of spermatogenesis, making this formula appropriate for men who want hormonal optimization without compromising fertility.

Individual results may vary. Benefits described are based on clinical and pharmacological evidence and do not constitute a guarantee of treatment outcomes. All treatment requires evaluation and approval by a licensed provider.

Simple. Medical.

Personalized.

Medical intake

Answer a few online questions about your health history, lifestyle, & goals. No clinic visits required.

Provider evaluation

A licensed medical provider reviews your intake to determine the safest, personalized treatment.

Personalized plan

Custom treatment plan built around your unique health needs, goals, medical history, & biology.

Ongoing support

Stay connected with your care team for follow-ups, adjustments, & expert answers 100% online.

All eligibility is reviewed by a licensed medical professional

FAQs

What is Gonadorelin / Pregnenolone / DHEA Troche?

A compounded sublingual troche combining gonadorelin, pregnenolone, and DHEA to support the body's own HPG axis, steroidogenic precursor supply, and adrenal androgen output simultaneously. Doses are listed on your order form.

Who should use Gonadorelin / Pregnenolone / DHEA Troche?

Men experiencing age-related hormonal decline including low-normal testosterone, low DHEA-S, fatigue, reduced motivation, and decreased sexual drive who prefer natural precursor and axis support over direct testosterone replacement. Provider evaluation and baseline labs are required.

Does Gonadorelin / Pregnenolone / DHEA Troche require a prescription?

Yes. Gonadorelin is a prescription-only peptide. This compounded troche requires a valid prescription from a licensed provider.

What are the possible side effects?

Gonadorelin: mild flushing, headache, or scrotal sensitivity with increased LH stimulation. Pregnenolone and DHEA: acne, oily skin, mild androgenic or estrogenic effects, and elevated estradiol in susceptible individuals. Hormone monitoring manages these effectively.

Who Should Not Use Gonadorelin / Pregnenolone / DHEA Troche?

Not for patients with primary hypogonadism (testicular failure), as gonadorelin requires functional Leydig cells to drive testosterone production. Not for men with hormone-sensitive malignancies or active oncological treatment without specialist clearance.

Are there any drug interactions?

DHEA and pregnenolone may affect estradiol levels in patients on aromatase inhibitors or estrogen-modulating therapies. Gonadorelin activity is blunted by concurrent exogenous testosterone or anabolic steroid use. Disclose all medications to your provider.

Is Gonadorelin / Pregnenolone / DHEA Troche safe if I have a pre-existing medical condition?

Patients with hormone-sensitive conditions, adrenal disorders, or hepatic impairment require provider evaluation before starting. Baseline and follow-up labs including testosterone, DHEA-S, estradiol, and LH are recommended throughout treatment.

Contact Us

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Hours

Monday–Saturday, 10am–8pm ET

Text or Call

Hours

Monday–Saturday, 10am–8pm ET

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Physician-supervised. Delivered to your door.

No clinic visits required.

  • Licensed Provider

  • Licensed Pharmacy

  • HIPAA Compliant

  • LegitScript Certified

The information and clinical services described on this website are for educational and informational purposes only and are not intended to diagnose, treat, cure, or prevent any disease. All treatments require evaluation and approval by a licensed healthcare provider through a telemedicine consultation. Treatment approval is not guaranteed. Individual results may vary, and treatments may carry risks and side effects. Certain compounded medications, wellness treatments, or off-label uses may not be evaluated by the U.S. Food and Drug Administration (FDA) for safety, effectiveness, or quality unless explicitly stated. Testosterone Shots provides telehealth consultations, clinical review, care coordination, lab-related services, membership services, and ongoing treatment management. Testosterone Shots is not a pharmacy and does not manufacture, compound, dispense, sell, handle, warehouse, ship, or collect payment for prescription medication. Testosterone Shots collects payment only for consultations, clinical review, care coordination, lab-related services, membership services, and other non-pharmacy services. If treatment is approved, your prescription may be sent to a licensed pharmacy partner. The pharmacy contacts you directly to complete medication payment and shipping. Services are provided by licensed physicians, nurse practitioners, and/or other licensed healthcare providers in states where they are authorized to practice. This service is not intended for medical emergencies. If you are experiencing an emergency, call 911 or seek immediate medical care. We take reasonable measures to protect personal health information in accordance with applicable privacy laws, including HIPAA. By using this website or its services, you agree to our Terms of Service, Privacy Policy, Notice of Privacy Practices, Telehealth Consent, and Important Safety Information. You must be 18 years of age or older to use this service.