Detox + Cellular Energy
Glutathione + NAD+ Nasal Spray
A dual-active nasal spray delivering your body's master antioxidant and the cellular energy coenzyme NAD+ directly through the nasal mucosa for rapid systemic absorption and anti-aging support.
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Overview
Glutathione 200 mg/mL + NAD+ 200 mg/mL
Glutathione and NAD+ are two of the most studied compounds in longevity and cellular health research, and both decline significantly with age. Intranasal delivery bypasses the GI degradation that limits oral bioavailability of glutathione and provides a practical, needle-free route for NAD+ delivery alongside its antioxidant partner.
Mechanism of Action
Glutathione is the body's primary intracellular antioxidant, neutralizing reactive oxygen species, regenerating vitamins C and E, and serving as the rate-limiting substrate for the liver's phase II detoxification enzymes. NAD+ is the central coenzyme in mitochondrial energy production, serving as an electron carrier in the electron transport chain and as a substrate for sirtuins, PARP DNA repair enzymes, and CD38, all of which are implicated in aging biology. Intranasal absorption delivers both actives through the highly vascularized nasal mucosa into systemic circulation, bypassing first-pass hepatic degradation.
Nasal Spray
Administered intranasal delivery bypasses first-pass hepatic degradation.
Information presented here is for educational purposes only and not intended to replace or substitute guidance from a healthcare provider. Compounded medications are not FDA-approved nor evaluated by the FDA for safety, efficacy, or quality.
Benefits
Energy
NAD+ replenishes the mitochondrial coenzyme pool required for ATP synthesis, directly supporting cellular energy production that declines with age.
Detox
Glutathione supports hepatic phase II detoxification and directly neutralizes reactive oxygen species that accumulate from environmental, metabolic, and physiological stress.
Healing
NAD+ is the substrate for PARP DNA repair enzymes that correct oxidative DNA damage, while glutathione reduces the oxidative burden that causes that damage in the first place.
Immune Function
Glutathione is essential for lymphocyte proliferation and natural killer cell function, fueling the immune response that declines with oxidative stress and aging.
Brain Focus and Clarity
Both NAD+ and glutathione support neuronal energy metabolism and protect against the oxidative and inflammatory damage that drives cognitive aging.
Individual results may vary. Benefits described are based on clinical and pharmacological evidence and do not constitute a guarantee of treatment outcomes. All treatment requires evaluation and approval by a licensed provider.
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Medical intake
Answer a few online questions about your health history, lifestyle, & goals. No clinic visits required.
Provider evaluation
A licensed medical professional reviews your intake to determine the safest, personalized treatment.
Personalized plan
Custom treatment plan built around your unique health needs, goals, medical history, & biology.
Ongoing support
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FAQs
What is Glutathione + NAD+ Nasal Spray?
A compounded intranasal spray delivering glutathione, the body's master antioxidant, alongside NAD+, the central coenzyme of mitochondrial energy production and cellular repair, through the nasal mucosa for rapid systemic absorption.
Who should use Glutathione + NAD+ Nasal Spray?
Adults experiencing age-related decline in energy, cognitive clarity, detoxification capacity, or immune resilience who prefer a non-injectable delivery route for antioxidant and NAD+ support. Provider evaluation is recommended before starting.
Does Glutathione + NAD+ Nasal Spray require a prescription?
Yes. This is a compounded prescription nasal spray requiring a valid prescription from a licensed provider.
What are the possible side effects?
Mild nasal irritation, burning, or congestion are the most common effects of intranasal delivery and typically resolve with consistent use. Transient flushing or headache has been reported with NAD+ administration. Glutathione at therapeutic doses is generally very well tolerated systemically.
Who should not use Glutathione + NAD+ Nasal Spray?
Not for patients with known hypersensitivity to glutathione or NAD+. Patients undergoing active chemotherapy should consult their oncologist before using glutathione, as it may reduce the oxidative cytotoxic mechanism of certain chemotherapy agents.
Are there any drug interactions?
Glutathione may reduce the effectiveness of certain platinum-based chemotherapy agents. NAD+ precursors and supplemental NAD+ used concurrently may have additive effects. Disclose all current supplements and medications to your provider.
Is Glutathione + NAD+ Nasal Spray safe if I have a pre-existing medical condition?
Patients with active malignancy require oncologist evaluation before starting glutathione. Patients with liver disease may benefit most from glutathione support and are generally good candidates with provider oversight.
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The information and clinical services described on this website are for educational and informational purposes only and are not intended to diagnose, treat, cure, or prevent any disease. All treatments require evaluation and approval by a licensed healthcare provider through a telemedicine consultation. Treatment approval is not guaranteed. Individual results may vary, and treatments may carry risks and side effects. Certain compounded medications, wellness treatments, or off-label uses may not be evaluated by the U.S. Food and Drug Administration (FDA) for safety, effectiveness, or quality unless explicitly stated. Testosterone Shots provides telehealth consultations, clinical review, care coordination, lab-related services, membership services, and ongoing treatment management. Testosterone Shots is not a pharmacy and does not manufacture, compound, dispense, sell, handle, warehouse, ship, or collect payment for prescription medication. Testosterone Shots collects payment only for consultations, clinical review, care coordination, lab-related services, membership services, and other non-pharmacy services. If treatment is approved, your prescription may be sent to a licensed pharmacy partner. The pharmacy contacts you directly to complete medication payment and shipping. Services are provided by licensed physicians, nurse practitioners, and/or other licensed healthcare providers in states where they are authorized to practice. This service is not intended for medical emergencies. If you are experiencing an emergency, call 911 or seek immediate medical care. We take reasonable measures to protect personal health information in accordance with applicable privacy laws, including HIPAA. By using this website or its services, you agree to our Terms of Service, Privacy Policy, Notice of Privacy Practices, Telehealth Consent, and Important Safety Information. You must be 18 years of age or older to use this service.