Stop Hair Damage
Dutasteride
The most potent available oral DHT blocker, suppressing the androgen responsible for follicular miniaturization.
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Overview
Pharmacology
Dutasteride is a dual-isoenzyme 5-alpha reductase inhibitor that blocks both type I and type II enzymes, reducing serum DHT by up to 90 percent. Finasteride inhibits only type II and reduces DHT by approximately 70 percent. This difference is clinically significant in patients with inadequate response to finasteride or more aggressive androgenetic alopecia.
Mechanism of Action
Dutasteride competitively and irreversibly inhibits both type I and type II 5-alpha reductase isoenzymes, preventing testosterone conversion to dihydrotestosterone in scalp follicles, skin, and prostate tissue. The resulting suppression of intrafollicular DHT halts follicular miniaturization and allows existing follicles to return to normal growth cycles.
Oral Capsule
Taken orally once daily.
Information presented here is for educational purposes only and not intended to replace or substitute guidance from a healthcare provider. Compounded medications are not FDA-approved nor evaluated by the FDA for safety, efficacy, or quality.
Benefits
Hair
Suppresses DHT more completely than finasteride through dual-isoenzyme blockade, halting follicular miniaturization and supporting recovery of existing follicles.
Prevention
Deeper DHT suppression preserves more follicular reserve over time, particularly valuable in patients with more aggressive or earlier-onset androgenetic alopecia.
Sexual Health
Reduces prostate tissue DHT stimulation, providing symptomatic relief in patients with concurrent benign prostatic hyperplasia.
Confidence
Clinically superior DHT suppression for patients who have plateaued on finasteride or are seeking a comprehensive pharmacological hair loss prevention.
Individual results may vary. Benefits described are based on clinical and pharmacological evidence and do not constitute a guarantee of treatment outcomes. All treatment requires evaluation and approval by a licensed provider.
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Medical intake
Answer a few online questions about your health history, lifestyle, & goals. No clinic visits required.
Provider evaluation
A licensed medical provider reviews your intake to determine the safest, personalized treatment.
Personalized plan
Custom treatment plan built around your unique health needs, goals, medical history, & biology.
Ongoing support
Stay connected with your care team for follow-ups, adjustments, & expert answers 100% online.
All eligibility is reviewed by a licensed medical professional
FAQs
What is Dutasteride?
Dutasteride is a prescription therapy used for hair loss support.
Who should use Dutasteride?
Patients seeking support for hair loss support may qualify after evaluation by a licensed provider.
Does Dutasteride require a prescription?
Yes. Dutasteride is an FDA-approved prescription medication for benign prostatic hyperplasia and is prescribed off-label for androgenetic alopecia. A valid prescription from a licensed provider is required.
What are the possible side effects?
Decreased libido, erectile dysfunction, reduced ejaculate volume, and gynecomastia are the most common side effects. These are generally mild and may resolve over time, though persistent side effects have been reported. Post-finasteride-like persistent sexual side effects have been reported with dutasteride in a small subset of patients.
Who Should Not Use Dutasteride?
Do not take if pregnant, breastfeeding, or if you are a woman of childbearing potential. Dutasteride may cause fetal harm. Not for patients with known hypersensitivity to dutasteride or other 5-alpha reductase inhibitors, or significant hepatic impairment.
Are there any drug interactions?
Dutasteride is metabolized by CYP3A4. Inhibitors including ritonavir, ketoconazole, and verapamil can significantly increase dutasteride blood levels. Patients on these medications require provider evaluation before starting.
Is Dutasteride safe if I have a pre-existing medical condition?
Patients with hepatic impairment require dose reduction and close monitoring. Patients with prostate cancer history require urologist evaluation, as dutasteride reduces PSA levels and can affect monitoring accuracy. Regular PSA and liver function monitoring is recommended.
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The information and clinical services described on this website are for educational and informational purposes only and are not intended to diagnose, treat, cure, or prevent any disease. All treatments require evaluation and approval by a licensed healthcare provider through a telemedicine consultation. Treatment approval is not guaranteed. Individual results may vary, and treatments may carry risks and side effects. Certain compounded medications, wellness treatments, or off-label uses may not be evaluated by the U.S. Food and Drug Administration (FDA) for safety, effectiveness, or quality unless explicitly stated. Testosterone Shots provides telehealth consultations, clinical review, care coordination, lab-related services, membership services, and ongoing treatment management. Testosterone Shots is not a pharmacy and does not manufacture, compound, dispense, sell, handle, warehouse, ship, or collect payment for prescription medication. Testosterone Shots collects payment only for consultations, clinical review, care coordination, lab-related services, membership services, and other non-pharmacy services. If treatment is approved, your prescription may be sent to a licensed pharmacy partner. The pharmacy contacts you directly to complete medication payment and shipping. Services are provided by licensed physicians, nurse practitioners, and/or other licensed healthcare providers in states where they are authorized to practice. This service is not intended for medical emergencies. If you are experiencing an emergency, call 911 or seek immediate medical care. We take reasonable measures to protect personal health information in accordance with applicable privacy laws, including HIPAA. By using this website or its services, you agree to our Terms of Service, Privacy Policy, Notice of Privacy Practices, Telehealth Consent, and Important Safety Information. You must be 18 years of age or older to use this service.