Pain + Musculoskeletal
Cyclobenzaprine + Diclofenac + Lidocaine Cream
Three prescription ingredients in one cream — a muscle relaxant, an anti-inflammatory, and a nerve pain blocker — applied directly to the source of pain. Faster relief, no pills, no systemic side effects.
No Insurance Required
Ships from USA Pharmacy
Free Medical Consultation
No Subscription Required
Licensed Provider
Licensed Pharmacy
HIPAA Compliant
LegitScript Certified
Overview
Cyclobenzaprine + Diclofenac + Lidocaine
Three independent mechanisms targeting musculoskeletal pain simultaneously: skeletal muscle spasm, local tissue inflammation, and afferent nerve pain signaling. Topical delivery concentrates active levels at the site of pain while minimizing systemic exposure relative to oral equivalents.
Mechanism of Action
Cyclobenzaprine acts centrally at the brainstem to reduce tonic somatic motor activity, relieving skeletal muscle spasm without acting directly at the neuromuscular junction. Diclofenac inhibits cyclooxygenase-1 and COX-2, blocking prostaglandin synthesis and reducing the local inflammatory cascade that drives pain, heat, and swelling at injury sites. Lidocaine stabilizes neuronal membranes by reversibly blocking voltage-gated sodium channels, preventing the initiation and conduction of afferent pain signals from the affected tissue.
Topical Application
Applied to affected areas as directed.
Information presented here is for educational purposes only and not intended to replace or substitute guidance from a healthcare provider. Compounded medications are not FDA-approved nor evaluated by the FDA for safety, efficacy, or quality.
Benefits
Pain Relief
Targeting muscle spasm, inflammation, and nerve pain signals all at once, instead of just masking symptoms.
Reducing Inflammation
Gets to the root of what's causing the pain — shutting down the inflammatory process in the tissue itself, not just dulling the sensation from the outside.
Faster Healing
When inflammation and muscle spasm are controlled, your body can actually repair the damaged tissue. Less interference, faster recovery.
Muscle Relaxation
Breaks the pain-spasm cycle — where a muscle injury causes spasm, spasm causes more pain, and pain causes more spasm. Stops it at the source.
Individual results may vary. Benefits described are based on clinical and pharmacological evidence and do not constitute a guarantee of treatment outcomes. All treatment requires evaluation and approval by a licensed provider.
Simple. Medical. Personalized.
Medical intake
Answer a few online questions about your health history, lifestyle, and goals. No clinic visits required.
Provider evaluation
A licensed medical professional reviews your intake and determines the safest, personalized treatment.
Personalized plan
Custom treatment plan built around your unique health needs, goals, medical history, and biology.
Ongoing support
Stay connected with your care team for follow-ups, adjustments, and expert answers 100% online.
FAQs
What is Cyclobenzaprine Diclofenac Lidocaine?
Cyclobenzaprine Diclofenac Lidocaine is a prescription therapy used for pain and muscle support.
Who should use Cyclobenzaprine Diclofenac Lidocaine?
Patients seeking support for pain and muscle support may qualify after evaluation by a licensed provider.
Does Cyclobenzaprine / Diclofenac / Lidocaine Cream require a prescription?
Yes. All three actives are prescription-only at these concentrations. A valid prescription from a licensed provider is required.
What are the possible side effects?
Local skin reactions including redness, burning, or itching at the application site are the most common. Cyclobenzaprine may cause mild drowsiness with significant systemic absorption. Diclofenac applied over large areas or under occlusion carries a low risk of systemic NSAID effects. Lidocaine at therapeutic topical doses is well tolerated, but systemic toxicity (dizziness, tinnitus) is possible with excessive application.
Who should not use Cyclobenzaprine / Diclofenac / Lidocaine Cream?
Not for patients with known hypersensitivity to any component, active NSAIDs, or amide-type local anesthetics. Avoid in patients with severe hepatic impairment, aspirin-sensitive asthma, or active peptic ulcer disease. Not for use during the third trimester of pregnancy due to the diclofenac component.
Are there any drug interactions?
Diclofenac (topical) may interact with oral anticoagulants including warfarin and other NSAIDs at significant systemic absorption levels. Concurrent systemic cyclobenzaprine or CNS depressants are contraindicated due to additive sedative effects. Patients on MAO inhibitors must not use cyclobenzaprine-containing products.
Is Cyclobenzaprine / Diclofenac / Lidocaine Cream safe if I have a pre-existing medical condition?
Patients with hepatic impairment should use with caution given diclofenac's hepatic metabolism — liver function monitoring may be recommended. Patients with cardiovascular disease or a history of GI ulcers should discuss the diclofenac component with their provider. Patients with a history of seizure disorder should disclose prior to cyclobenzaprine use.
Contact Us
Start Your Journey
Ready to Treat Pain at the Source?
Physician-prescribed. Delivered to your door. No clinic visits required.
Licensed Provider
Licensed Pharmacy
HIPAA Compliant
LegitScript Certified
© 2026 TestosteroneShots.com, PC
text (323)-283-9219
638 1/2 N. Robertson Blvd, West Hollywood, CA 90069
Legal
The information and clinical services described on this website are for educational and informational purposes only and are not intended to diagnose, treat, cure, or prevent any disease. All treatments require evaluation and approval by a licensed healthcare provider through a telemedicine consultation. Treatment approval is not guaranteed. Individual results may vary, and treatments may carry risks and side effects. Certain compounded medications, wellness treatments, or off-label uses may not be evaluated by the U.S. Food and Drug Administration (FDA) for safety, effectiveness, or quality unless explicitly stated. Testosterone Shots provides telehealth consultations, clinical review, care coordination, lab-related services, membership services, and ongoing treatment management. Testosterone Shots is not a pharmacy and does not manufacture, compound, dispense, sell, handle, warehouse, ship, or collect payment for prescription medication. Testosterone Shots collects payment only for consultations, clinical review, care coordination, lab-related services, membership services, and other non-pharmacy services. If treatment is approved, your prescription may be sent to a licensed pharmacy partner. The pharmacy contacts you directly to complete medication payment and shipping. Services are provided by licensed physicians, nurse practitioners, and/or other licensed healthcare providers in states where they are authorized to practice. This service is not intended for medical emergencies. If you are experiencing an emergency, call 911 or seek immediate medical care. We take reasonable measures to protect personal health information in accordance with applicable privacy laws, including HIPAA. By using this website or its services, you agree to our Terms of Service, Privacy Policy, Notice of Privacy Practices, Telehealth Consent, and Important Safety Information. You must be 18 years of age or older to use this service.