Dual Amino Acid + Nitric Oxide + Collagen
Bi-Amino
Boost nitric oxide, stimulate growth hormone, and rebuild collagen — two synergistic amino acids that also suppress HSV replication in one weekly injection.
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Overview
L-Arginine HCl / L-Lysine HCl
Bi-Amino combines two of the most clinically studied injectable amino acids in one formulation. L-arginine drives nitric oxide synthesis and growth hormone release. L-lysine provides the obligate substrate for collagen cross-linking, carnitine biosynthesis, and antiviral defense through arginine competition at shared cellular transporters. Together they address vascular health, connective tissue integrity, and immune function through complementary and partially synergistic mechanisms, while lysine's arginine-competition effect naturally modulates the HSV-permissive environment that arginine alone would create.
Mechanism of Action
L-arginine is converted by NOS enzymes to nitric oxide, activating soluble guanylate cyclase in vascular smooth muscle and driving vasodilation, tissue perfusion, and endothelial function. Arginine also inhibits hypothalamic somatostatin to increase pituitary GH pulse amplitude. L-lysine is the required substrate for lysyl hydroxylase in collagen proline and lysine hydroxylation, enabling collagen cross-linking and structural integrity. Lysine competitively inhibits arginine uptake at shared CAT-1/CAT-2 transporters, counterbalancing any excess arginine-driven HSV replication while preserving systemic nitric oxide activity. Lysine additionally provides substrate for carnitine synthesis via trimethyllysine, supporting mitochondrial fatty acid oxidation alongside arginine's mTORC1 activation of protein synthesis.
Injection
Administered intramuscularly ensures complete absorption and immediate bioavailability.
Information presented here is for educational purposes only and not intended to replace or substitute guidance from a healthcare provider. Compounded medications are not FDA-approved nor evaluated by the FDA for safety, efficacy, or quality.
Benefits
Nitric Oxide + GH
Arginine supplies the substrate for eNOS-driven vasodilation and inhibits somatostatin to support growth hormone release from the anterior pituitary.
Collagen Support
Lysine provides the obligate substrate for collagen cross-link hydroxylation, supporting skin, tendon, ligament, and vascular connective tissue integrity.
Balanced Amino Delivery
Lysine's competitive inhibition at shared arginine transporters naturally modulates excess arginine-driven HSV activity without eliminating systemic nitric oxide benefit.
Dual Metabolic Support
Arginine activates mTORC1 protein synthesis signaling; lysine provides trimethyllysine for carnitine biosynthesis and mitochondrial fatty acid oxidation.
Individual results may vary. Benefits described are based on clinical and pharmacological evidence and do not constitute a guarantee of treatment outcomes. All treatment requires evaluation and approval by a licensed provider.
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Medical intake
Answer a few online questions about your health history, lifestyle, & goals. No clinic visits required.
Provider evaluation
A licensed medical provider reviews your intake to determine the safest, personalized treatment.
Personalized plan
Custom treatment plan built around your unique health needs, goals, medical history, & biology.
Ongoing support
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All eligibility is reviewed by a licensed medical professional
FAQs
What is Bi-Amino Injection?
Bi-Amino Injection is a prescription therapy used for amino acid support.
Who should use Bi-Amino Injection?
Patients seeking support for amino acid support may qualify after evaluation by a licensed provider.
Does Bi-Amino require a prescription?
Yes. This is a compounded injectable preparation containing two prescription amino acid actives, requiring a valid prescription from a licensed provider.
What are the possible side effects?
The arginine component may cause transient flushing, mild hypotension, or nausea at higher doses. High-dose combined amino acids may cause GI discomfort, electrolyte shifts, or transient headache. Injection site reactions are the most common effect.
Who should not use Bi-Amino Injection?
Not for patients with urea cycle disorders, severe hepatic impairment, or lysinuric protein intolerance. Patients with hypotension require careful monitoring given arginine's vasodilatory activity. Do not take if pregnant or breastfeeding. Patients with a history of kidney stones should discuss lysine's calcium-absorption effects with their provider.
Are there any drug interactions?
Arginine may potentiate antihypertensives and PDE5 inhibitors. Concurrent potassium-sparing diuretics or ACE inhibitors increase hyperkalemia risk with arginine use. Lysine may reduce metformin absorption at shared intestinal transporters; patients on metformin should disclose this to their provider.
Is Bi-Amino Injection safe if I have a pre-existing medical condition?
Patients with cardiovascular disease, renal impairment, hepatic disease, or electrolyte disorders require individualized provider evaluation before starting. Diabetic patients should monitor blood glucose given arginine's insulin secretagogue activity.
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The information and clinical services described on this website are for educational and informational purposes only and are not intended to diagnose, treat, cure, or prevent any disease. All treatments require evaluation and approval by a licensed healthcare provider through a telemedicine consultation. Treatment approval is not guaranteed. Individual results may vary, and treatments may carry risks and side effects. Certain compounded medications, wellness treatments, or off-label uses may not be evaluated by the U.S. Food and Drug Administration (FDA) for safety, effectiveness, or quality unless explicitly stated. Testosterone Shots provides telehealth consultations, clinical review, care coordination, lab-related services, membership services, and ongoing treatment management. Testosterone Shots is not a pharmacy and does not manufacture, compound, dispense, sell, handle, warehouse, ship, or collect payment for prescription medication. Testosterone Shots collects payment only for consultations, clinical review, care coordination, lab-related services, membership services, and other non-pharmacy services. If treatment is approved, your prescription may be sent to a licensed pharmacy partner. The pharmacy contacts you directly to complete medication payment and shipping. Services are provided by licensed physicians, nurse practitioners, and/or other licensed healthcare providers in states where they are authorized to practice. This service is not intended for medical emergencies. If you are experiencing an emergency, call 911 or seek immediate medical care. We take reasonable measures to protect personal health information in accordance with applicable privacy laws, including HIPAA. By using this website or its services, you agree to our Terms of Service, Privacy Policy, Notice of Privacy Practices, Telehealth Consent, and Important Safety Information. You must be 18 years of age or older to use this service.