Tirzepatide Sublingual Drops

Tirzepatide sublingual drops are a compounded oral medication taken as 0.5mL under the tongue daily. They may help regulate blood sugar, reduce appetite, and lower inflammation by activating two key receptors in the body — leading to better glucose control and weight management. As a compounded preparation, this product is not FDA-approved.

Overview

Tirzepatide sublingual drops deliver a GLP-1 receptor agonist directly through the mucosa under the tongue, allowing the active compound to absorb into systemic circulation while bypassing first-pass hepatic metabolism. This makes sublingual drops a practical daily alternative to weekly injectable tirzepatide for patients who prefer an oral route of administration.

Available through a valid prescription from a licensed healthcare provider via telemedicine consultation. Compounded by Strive Pharmacy.

Adults seeking blood sugar regulation through a daily oral option

Those looking to reduce appetite without weekly injections

Patients who prefer a needle-free route of administration

A convenient sublingual alternative to injectable tirzepatide

Dual-receptor action. Without the needle.

Formulation & Ingredient Breakdown

Tirzepatide

Dual GIP / GLP-1 Receptor Agonist

Activates both GIP and GLP-1 receptors simultaneously — stimulating insulin secretion, suppressing glucagon, and slowing gastric emptying. Dual-receptor activation produces greater reductions in blood sugar and body weight than single-receptor agonism alone.

Sublingual Delivery

0.5mL Once Daily

Administered under the tongue once daily. Sublingual absorption bypasses the gastrointestinal tract and first-pass liver metabolism, delivering the active compound directly into circulation.

Compounded Preparation

Strive Pharmacy

Prepared specifically for patients with a valid prescription following a telemedicine consultation. Not an FDA-approved drug product. Individual formulation and concentration determined by the prescribing provider.

Glucose & Appetite Regulation

Tirzepatide works by mimicking both GIP and GLP-1 — two hormones naturally released after eating. Together they signal the brain to reduce hunger, slow digestion, and support blood sugar regulation without acting as insulin.

Anti-Inflammatory Support

Dual GIP/GLP-1 receptor agonism has been associated with reductions in systemic inflammation markers. Tirzepatide may help lower inflammation as part of its broader metabolic effects.

All eligibility is reviewed by a licensed medical professional.

Simple. Medical. Personalized.

Medical intake

Answer a few online questions about your health history, lifestyle, and goals — no clinic visits required.

Provider evaluation

A licensed medical professional reviews your intake and determines the safest, most effective option for you.

Personalized plan

Custom treatment plan built around your unique health needs, goals, medical history, and biology.

Ongoing support

Stay connected with your care team for follow-ups, adjustments, and expert answers — all online.

FAQs

Dosage & Administration

Directions: Take 0.5mL drops under the tongue daily. Hold under the tongue for 30–60 seconds before swallowing. Do not eat or drink for 15 minutes after administration.

Form: Sublingual liquid drops  ·  Dose: 0.5mL  ·  Frequency: Once daily  ·  Route: Sublingual

Dosage is determined by your prescribing provider. Do not adjust without medical guidance.

Precautions & Side Effects

Tirzepatide is a prescription-only medication and requires evaluation by a licensed healthcare provider. It is not appropriate for individuals with a personal or family history of medullary thyroid carcinoma or multiple endocrine neoplasia syndrome type 2. Common side effects may include nausea, reduced appetite, and mild gastrointestinal symptoms, particularly when starting treatment.

Storage

Store tirzepatide sublingual drops in the refrigerator between 36°F–46°F (2°C–8°C). Keep the bottle tightly closed and away from direct light. Do not freeze. Once opened, use within the timeframe specified by your compounding pharmacy. Keep out of reach of children.

The information and products provided on this website are for educational and wellness purposes only and are not intended to diagnose, treat, cure, or prevent any disease. All treatments require evaluation and approval by a licensed healthcare provider through a telemedicine consultation. Individual results may vary, and products carry potential risks and side effects. Certain products may not be evaluated by the U.S. Food and Drug Administration (FDA) unless explicitly stated. Services are provided by licensed physicians and nurse practitioners in states where they are authorized to practice, including California, Florida, Nevada, and other participating states. This service is not intended for medical emergencies. If you are experiencing an emergency, call 911 or seek immediate medical care. We take reasonable measures to protect personal health information in accordance with applicable privacy laws, including HIPAA. By using this website or its services, you agree to our Terms of Service, Privacy Policy, and Telehealth Consent. You must be 18 years of age or older to use this service.