Semaglutide Sublingual Drops

Semaglutide sublingual drops are a compounded oral medication taken as 0.5mL under the tongue daily. They may help regulate blood sugar, reduce appetite, and lower inflammation by activating a key receptor in the body — leading to better glucose control and weight management. As a compounded preparation, this product is not FDA-approved.

Overview

Semaglutide sublingual drops deliver a GLP-1 receptor agonist directly through the mucosa under the tongue, allowing the active compound to absorb into systemic circulation while bypassing first-pass hepatic metabolism. This makes sublingual drops a practical daily alternative to weekly injectable semaglutide for patients who prefer an oral route of administration.

Available through a valid prescription from a licensed healthcare provider via telemedicine consultation. Compounded by Strive Pharmacy.

Adults seeking blood sugar regulation through a daily oral option

Those looking to reduce appetite without weekly injections

Patients who prefer a needle-free route of administration

A convenient sublingual alternative to injectable semaglutide

Weight management. Without the needle.

Formulation & Ingredient Breakdown

Semaglutide

GLP-1 Receptor Agonist

Activates GLP-1 receptors to stimulate glucose-dependent insulin secretion, suppress glucagon secretion, and slow gastric emptying — reducing appetite and supporting weight management.

Sublingual Delivery

0.5mL Once Daily

Administered under the tongue once daily. Sublingual absorption bypasses the gastrointestinal tract and first-pass liver metabolism, delivering the active compound directly into circulation.

Compounded Preparation

Strive Pharmacy

Prepared specifically for patients with a valid prescription following a telemedicine consultation. Not an FDA-approved drug product. Individual formulation and concentration determined by the prescribing provider.

Glucose & Appetite Regulation

Semaglutide works by mimicking GLP-1, a hormone naturally released after eating. It signals the brain to reduce hunger, slows digestion to promote satiety, and supports blood sugar regulation without acting as insulin.

Anti-Inflammatory Support

GLP-1 receptor agonism has been associated with reductions in systemic inflammation markers in clinical research. Semaglutide may help lower inflammation as part of its broader metabolic effects.

All eligibility is reviewed by a licensed medical professional.

Simple. Medical. Personalized.

Medical intake

Answer a few online questions about your health history, lifestyle, and goals — no clinic visits required.

Provider evaluation

A licensed medical professional reviews your intake and determines the safest, most effective option for you.

Personalized plan

Custom treatment plan built around your unique health needs, goals, medical history, and biology.

Ongoing support

Stay connected with your care team for follow-ups, adjustments, and expert answers — all online.

FAQs

Dosage & Administration

Directions: Take 0.5mL drops under the tongue daily. Hold under the tongue for 30–60 seconds before swallowing. Do not eat or drink for 15 minutes after administration.

Form: Sublingual liquid drops  ·  Dose: 0.5mL  ·  Frequency: Once daily  ·  Route: Sublingual

Dosage is determined by your prescribing provider. Do not adjust without medical guidance.

Precautions

Inform your provider of all current medications and medical conditions before starting. Do not use alongside injectable semaglutide or other GLP-1 receptor agonists. Not recommended during pregnancy or breastfeeding.

Common side effects associated with GLP-1 therapy include nausea, vomiting, diarrhea, and abdominal discomfort — particularly when beginning treatment. Contact your provider if symptoms are severe or persistent.

This is a compounded preparation and is not FDA-approved. Individual results may vary.

Storage

Store as directed by Strive Pharmacy — typically refrigerated at 36–46°F (2–8°C), away from light and moisture. Keep out of reach of children.

Do not use if the solution appears discolored or contains visible particles. Follow all storage and disposal instructions provided with your order.

The information and products provided on this website are for educational and wellness purposes only and are not intended to diagnose, treat, cure, or prevent any disease. All treatments require evaluation and approval by a licensed healthcare provider through a telemedicine consultation. Individual results may vary, and products carry potential risks and side effects. Certain products may not be evaluated by the U.S. Food and Drug Administration (FDA) unless explicitly stated. Services are provided by licensed physicians and nurse practitioners in states where they are authorized to practice, including California, Florida, Nevada, and other participating states. This service is not intended for medical emergencies. If you are experiencing an emergency, call 911 or seek immediate medical care. We take reasonable measures to protect personal health information in accordance with applicable privacy laws, including HIPAA. By using this website or its services, you agree to our Terms of Service, Privacy Policy, and Telehealth Consent. You must be 18 years of age or older to use this service.