Skincare + Anti-Aging

Radiance

A prescription morning cream that brightens, firms, and protects with four synergistic actives in one daily application.

  • No Insurance Required

  • Ships From USA Pharmacy

  • Free Medical Consultation

  • No Subscription Required

  • Licensed Provider

  • Licensed Pharmacy

  • HIPAA Compliant

  • LegitScript Certified

Overview

Pharmacology

Azelaic Acid + Estriol

Vitamin C + Hyaluronic Acid

Mechanism of Action

Azelaic acid inhibits tyrosinase to reduce pigmentation and normalize cell turnover. Estriol supports collagen and hyaluronic acid synthesis in hormonally aging skin. Vitamin C neutralizes free radicals and brightens uneven tone. Hyaluronic acid draws moisture into the epidermis, anchoring all four actives in a hydrated skin environment.

Topical

Applied to face and neck as directed

Information presented here is for educational purposes only and not intended to replace or substitute guidance from a healthcare provider. Compounded products are not FDA-approved nor evaluated by the FDA for safety, efficacy, or quality.

Benefits

Azelaic Acid

Inhibits tyrosinase to reduce hyperpigmentation and melasma, normalizes keratinocyte turnover for smoother texture, and provides mild anti-inflammatory and antibacterial effects.

Estriol

The gentlest topical estrogen. Supports collagen and hyaluronic acid synthesis, improves epidermal thickness, and restores plumpness in hormonally aging skin.

Vitamin C

Neutralizes UV-generated free radicals, brightens uneven tone by interrupting melanin synthesis, and regenerates vitamin E to extend antioxidant protection throughout the day.

Hyaluronic Acid

Draws moisture into the epidermis, plumping fine lines and anchoring the formula's actives in a hydrated skin environment.

Synergistic Action

Four complementary mechanisms in one morning application. No need to layer multiple separate products.

These statements have not been evaluated by the U.S. Food and Drug Administration and should not be interpreted as medical advice or a guarantee of treatment outcomes.

Simple. Medical. Personalized.

Medical intake

Answer a few online questions about your health history, lifestyle, & goals. No clinic visits required.

Provider evaluation

A licensed medical professional reviews your intake to determine the safest, personalized treatment.

Personalized plan

Custom treatment plan built around your unique health needs, goals, medical history, & biology.

Ongoing support

Stay connected with your care team for follow-ups, adjustments, & expert answers 100% online.

What Patients Are Experiencing

"My skin is visibly brighter and firmer after six weeks. I had been layering four separate products before. One application now and the results are better."

— Donna F.*

"The estriol component made a real difference after menopause. Skin plumpness and moisture came back in a way nothing over the counter ever achieved."

— Patricia W.*

"Radiance is the first formula where I noticed a visible tone improvement within a month of consistent daily use."

— Sarah L.*

*Individual experiences may vary. Not all patients will have the same outcomes.

FAQs

Does Radiance require a prescription?

Yes. Radiance contains estriol, a prescription-only topical estrogen. The full process, including intake and provider review, is completed entirely online. No clinic visits required.

What are the possible side effects?

Mild skin irritation, redness, or sensitivity may occur initially. Estriol at topical doses carries low systemic risk but should be disclosed during hormone monitoring.

Who Should Not Use Radiance?

Not recommended during pregnancy. Avoid in patients with estrogen-sensitive cancers. Not for use on broken, infected, or actively irritated skin.

Are there any drug interactions?

Topical estriol may interact with systemic hormonal therapies. Disclose all current hormone treatments to your provider, including TRT, HRT, and thyroid medications.

Is Radiance safe if I have a pre-existing medical condition?

Patients with a history of estrogen-sensitive cancers, breast cancer, or cardiovascular disease require provider evaluation before use. Topical estriol carries low systemic absorption at standard doses, but all current hormone treatments — including HRT, TRT, and thyroid medications — must be disclosed at intake. Daily SPF 30 or higher is required throughout treatment.

Start Your Journey

Ready for Prescription-Strength Radiance Every Morning?

Physician-supervised compounded skincare delivered to your door. No clinic visits required.

  • Licensed Provider

  • Licensed Pharmacy

  • HIPAA Compliant

  • LegitScript Certified

The information and products provided on this website are for educational and wellness purposes only and are not intended to diagnose, treat, cure, or prevent any disease. All treatments require evaluation and approval by a licensed healthcare provider through a telemedicine consultation. Individual results may vary, and products carry potential risks and side effects. Certain products may not be evaluated by the U.S. Food and Drug Administration (FDA) unless explicitly stated. Services are provided by licensed physicians and nurse practitioners in states where they are authorized to practice, including California, Florida, Nevada, and other participating states. This service is not intended for medical emergencies. If you are experiencing an emergency, call 911 or seek immediate medical care. We take reasonable measures to protect personal health information in accordance with applicable privacy laws, including HIPAA. By using this website or its services, you agree to our Terms of Service, Privacy Policy, and Telehealth Consent. You must be 18 years of age or older to use this service. We do not manufacture, handle, or ship medications.