
Ozempic (semaglutide) is an FDA-approved subcutaneous GLP-1 receptor agonist indicated to improve glycemic control in adults with type 2 diabetes mellitus, and to reduce the risk of major adverse cardiovascular events in adults with type 2 diabetes and established cardiovascular disease. Each 4mg pen delivers 0.5mg once weekly for 8 weeks. Four needles are included.
Adults with type 2 diabetes needing improved glycemic control
Adults with T2D and established cardiovascular disease
Patients seeking HbA1c reduction through once-weekly injection
Those looking to reduce major adverse cardiac events




Dose: 0.5mg subcutaneous injection once weekly for 8 weeks. Administer in the abdomen, thigh, or upper arm. Rotate injection sites with each dose. May be administered with or without meals.
Pen total: 4mg · Per dose: 0.5mg · Route: Subcutaneous only · Needles included: 4
Do not adjust your dose without guidance from your prescribing provider.
Inform your provider of all current medications and medical conditions before starting. Concomitant use with other GLP-1 receptor agonists is not recommended. Use caution in patients with a history of diabetic retinopathy — rapid improvement in glycemic control has been associated with worsening retinopathy.
Most common adverse reactions (≥5% in clinical trials): nausea, vomiting, diarrhea, abdominal pain, constipation. These are primarily gastrointestinal in nature and tend to diminish over time.
Before first use: Refrigerate at 36–46°F (2–8°C). Do not freeze. Protect from light. Keep the cap on.
After first use: Store at room temperature up to 86°F (30°C) or refrigerated for up to 56 days. Discard if the solution is not clear and colorless. Dispose of used needles in an approved sharps container.

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