
NAD⁺ (Nicotinamide Adenine Dinucleotide) is a foundational coenzyme found in every cell of the body, playing a critical role in energy metabolism, DNA repair, and the activation of pathways associated with healthy aging. As we age, NAD⁺ levels naturally decline — a process accelerated by chronic stress and metabolic imbalance — leaving cells less equipped to perform at their best.
Primary cellular coenzyme for energy production
Supports mitochondrial function and ATP generation
Involved in DNA repair and cell recovery
Boosts metabolic efficiency and antioxidant activity
Essential for sirtuin activation (longevity pathways)




Directions: Take half tablet under the tongue daily. Allow to dissolve completely before swallowing. Do not adjust your dose without guidance from your prescribing provider.
Form: Sublingual Tablet
Dose: Half tablet daily
Route: Sublingual (under the tongue)
Pharmacy Strive: Pharmacy
Prescription: Required
Sublingual administration allows NAD⁺ to enter the bloodstream directly through the mucous membranes, bypassing digestive breakdown and delivering faster, more reliable absorption than oral capsules.
NAD⁺ (Nicotinamide Adenine Dinucleotide) is a coenzyme found in every living cell. It is essential for converting nutrients into usable cellular energy (ATP), regulating circadian rhythms, repairing damaged DNA, and activating sirtuins — a family of proteins strongly associated with longevity and cellular health.
NAD⁺ levels begin declining in your 30s and continue falling with age. Chronic stress, poor sleep, alcohol use, and metabolic dysfunction all accelerate this decline. By the time most people reach their 50s, cellular NAD⁺ levels can be less than half of what they were in youth — a primary driver of fatigue, cognitive slowing, and accelerated cellular aging.
Many patients report improvements in energy and mental clarity within the first 1–2 weeks of consistent daily use. Deeper benefits — including improved metabolic efficiency, recovery, and the longer-term effects of sirtuin activation — typically develop over 4–8 weeks of sustained use.
Your provider will help set realistic expectations based on your individual health baseline and goals.
Before beginning NAD⁺ therapy, inform your healthcare provider of all current medications, known allergies, and existing medical conditions. NAD⁺ is generally well tolerated, but individual responses vary.
Some patients experience mild, transient side effects at initiation — including nausea, flushing, or headache — which typically resolve as the body adjusts. If symptoms persist or worsen, contact your care team.
Do not use if you have a known hypersensitivity to niacin or niacinamide. Patients with active malignancies should consult their oncologist prior to use, as NAD⁺ precursors may influence cellular proliferation pathways.
Store at controlled room temperature, away from direct light, heat, and humidity. Keep in original packaging until use. Do not refrigerate unless specifically instructed by your pharmacy.
Keep out of reach of children. Dispose of unused medication in accordance with your pharmacy's or local authority's guidelines for pharmaceutical waste.
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