Place one troche under the tongue (sublingual) or between the gum and inner cheek (buccal) and allow it to dissolve slowly and completely — typically 10–20 minutes. Do not chew, swallow whole, or drink during dissolution, as this reduces mucosal absorption. Avoid eating or drinking for at least 5 minutes after the troche fully dissolves. Note: GHK-Cu Acetate has a characteristic blue hue — any temporary tinting of saliva during dissolution is normal and harmless. Timing and frequency are determined by your prescribing provider.

GHK-Cu Troche is not FDA-approved — all use is off-label and investigational. Informed consent is required. Not recommended in patients with Wilson's disease or copper metabolism disorders, active malignancy (angiogenic activity warrants oncology consultation), pregnancy, breastfeeding, or patients under 18. Copper-chelating agents (D-penicillamine, trientine) are contraindicated with concurrent use. Disclose all medications and health conditions to your provider before starting.

Store at room temperature, away from direct heat, humidity, and sunlight. Keep in the original sealed container — troches are moisture-sensitive. Do not refrigerate unless specifically directed, as condensation can degrade troche integrity. Keep out of reach of children. Use before the labeled expiration date.